| SC Mirandela - Santa Marta Penaguiao | 2 years ago | 2022-01-09:18:00 | 1 | |
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| Ferreira de Aves - Valadares Gaia | 2 years ago | 2022-01-09:18:00 | 2 | |
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| Gouveia - Gondomar | 2 years ago | 2022-01-09:18:00 | 2 | |
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| Heartland - Wikki Tourist | 2 years ago | 2022-01-09:18:00 | 1 | |
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| Enyimba - Shooting | 2 years ago | 2022-01-09:18:00 | 1 | |
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| Levadiakos - Kifisias | 2 years ago | 2022-01-09:18:00 | Postponed | |
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| Heartland - Wikki Tourist | 2 years ago | 2022-01-09:18:00 | FT:1 | |
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| Montpellier - Troyes | 2 years ago | 2022-01-09:17:00 | Postponed | |
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| Wolves - Sheffield Utd | 2 years ago | 2022-01-09:17:00 | 1 | |
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| Mogoditshane - BDF XI | 2 years ago | 2022-01-09:17:00 | 2 | |
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